COMPUTATIONAL METHODS FOR SELECTION OF FUNCTIONAL MONOMERS IN THE SYNTHESIS OF MOLECULARLY IMPRINTED POLYMER OXYTETRACYCLINE

Oxytetracycline is used to treat various disorders in poultry, particularly hens. Their use, however, may be connected with unsatisfactory residual levels food. Because the generally method for analyzing oxytetracycline residues expensive, unique preparation methods such as Molecularly Imprinted Polymer (MIP) approach have been developed. MIP one of most successful pre-analysis procedures extracting target analyte from complicated matrix. The significant aspect creating a selection functional monomers compatible monomer's physicochemical properties and template. PyRx Autodock apps are this study determine value binding affinity hydrogen bonding created between monomer According study, 5-[1-(2,3-dimethylphenyl]-1H-imidazole has lowest (-4.34 kcal/mol), indicating that template will interact well monomer.